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EVAYPA® (EYA-01) Supplement

EVAYPA® (EYA-01) Supplement

Reported in preclinical studies:

  • Promoted longitudinal skeletal growth
  • Increased growth hormone signaling
  • Enhanced IGF-1 activity
  • Upregulated IGFBP-3 expression
  • Activated JAK2/STAT5 signaling
  • Enhanced growth-plate development
  • Increased chondrocyte proliferation
  • Expanded hypertrophic growth-plate zones
  • Increased osteocalcin activity
  • Increased BMP-2 expression
  • Increased osteoblast proliferation
  • Enhanced collagen and ALP expression
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The Science Behind It

EVAYPA combines six research-selected ingredients that have been investigated in preclinical studies for longitudinal skeletal growth and growth-plate biology. Individual studies reported effects on longitudinal bone growth, growth hormone and IGF-1 signaling, IGFBP-3 expression, JAK2/STAT5 activation, BMP-2 expression, chondrocyte proliferation, growth-plate development, and osteogenic activity.

Rather than focusing on a single mechanism, EVAYPA brings together ingredients studied across several interconnected growth pathways. PCE, for example, was associated with increased GH, IGF-1, IGFBP-3 and JAK2/STAT5 signaling, while Allium macrostemon, Amomum villosum, velvet antler and Eleuthero were studied for effects involving the growth plate, IGF-1, BMP-2, chondrocyte activity or longitudinal bone growth.

Studies:

https://koreantk.com/ktkp2014/thesis/thesis-view.view?ctrlNo=DHBCBU_2003_v18n1_87&tempLang=en
https://patents.google.com/patent/KR100463263B1/en
https://pubmed.ncbi.nlm.nih.gov/19107743/
https://pubmed.ncbi.nlm.nih.gov/23297572/
https://www.sciencedirect.com/science/article/pii/S0254627213600540
https://pmc.ncbi.nlm.nih.gov/articles/PMC4921679/
https://pmc.ncbi.nlm.nih.gov/articles/PMC7700597/
https://pubmed.ncbi.nlm.nih.gov/33233332/
https://pmc.ncbi.nlm.nih.gov/articles/PMC12483234/
https://pubmed.ncbi.nlm.nih.gov/41026801/

Shipping & Returns

We offer tracked shipping on all orders.

All orders are processed by our careful fulfilment team within 24 business hours.

We are currently experiencing high volume of orders so delivery times, depending on your location, range from 5-13 business days.

We've made returning products super easy. Simply contact us info@evaypa.com and we'll handle everything

Is It Safe?

Ingredients













Frequently Asked Questions



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Every Ingredient Carefully Chosen

Every ingredient in our formula is there for a reason—and backed by peer-reviewed research, not marketing fluff. We don’t hide behind “proprietary blends” or vague labels. You get a clear, transparent list of clinically supported ingredients—each included at a meaningful dose.

Turmeric

Anti-Inflammatory

Black Pepper

Improves Absorption

Bee Propolis

Immune Support

Ginger

Digestive Support

Coconut Oil

Lipid Carrier

Vitamin C

Cartilage Support

Turmeric

Turmeric provides curcuminoids, including curcumin — the compounds responsible for its well-known anti-inflammatory properties. By helping support a healthy inflammatory response, curcumin can help reduce joint discomfort, stiffness and support easier everyday movement.

Black Pepper

Curcumin is naturally difficult for the body to absorb on its own. Our formula includes black pepper extract as a source of piperine, which can significantly increase curcumin absorption (up to 2000%) helping your body get more from every dose.

Bee Propolis

Bee propolis is a natural source of antioxidant and bioactive compounds that help support the body’s immune and inflammatory response. We include it to complement turmeric and provide additional whole-body support alongside the formula’s primary joint-focused ingredients.

Ginger

Ginger has a long history of use for both digestive comfort and inflammatory support. Alongside turmeric, it helps support a healthy inflammatory response while also helping make the formula gentler and more supportive of digestion.

Coconut Oil

Curcumin is fat-soluble, meaning it is better absorbed when consumed alongside fat. Coconut-derived MCT oil acts as a lipid carrier in the formula, helping create better conditions for your body to absorb and utilise the curcumin.

Vitamin C

Vitamin C does more than provide antioxidant support, it also contributes to normal collagen formation for the healthy function of cartilage. That makes it a natural addition to a formula designed to support both joint comfort and long-term joint health.

What Sets Our Turmeric Apart?

Most turmeric supplements on the market sound the same—but there are critical differences that affect how well they work in your body. Here’s why ours stands out:

Clinically Effective Dosage

We don’t just sprinkle in turmeric for the label, we use a high-potency extract standardized to 95% curcuminoids. This matches the clinical dose used in human studies for joint health, pain reduction, and systemic inflammation.

Enhanced Absorption with Black Pepper Extract

Curcumin (the active compound in turmeric) is notoriously hard for the body to absorb. That’s why we include black pepper extract, proven in clinical studies to boost absorption by up to 2000%.

Sustainably Sourced

Our turmeric is sourced from organically grown roots and extracted using a solvent-free, clean extraction method that preserves the full spectrum of beneficial compounds without the fillers, additives, or artificial preservatives you’ll find in cheaper alternatives.

Customer First Approach

Your satisfaction is our priority. Our dedicated support team is here to ensure you have a positive experience every step of the way.

200K+ Happy Customers

Excellent 4.9

What Real Customers Are Saying

I took Ibuprofen for over 40 years, trying to control my fibromyalgia and osteoarthritis pain. I knew I needed to stop taking them, but I just couldn't find anything else that worked. Until I started reading about Curcumin. When I found the supplement by Bioroot Labs, I felt it was manufactured in the best way possible, with additions that all the material I read said should be included. I have been taking 3 per day for 4 months now, and I am so happy to say that I am taking NO other pain medication and feel better than I have for many years. My pain and stiffness is not entirely gone, but I am definitely better than I ever was on Ibuprofen. I am a very satisfied customer!

Verified

Sandra Rideout

Before starting this amazing product I had had to give up my business ( upholstery) as I could no longer use my hands through swelling joints I could no longer wear my rings. I think I have been on it about 3 months now and I have my complete use of my hands back. All swelling has gone. Absolutely amazing. The dont click or feel gritty. Thank you

Verified

Tara Crow

I was diagnosed with polymyalgia rhuematica within 6 months I had developed severe ME or CFS. Over the following years I suffered pain and exhaustion and in 2016 eventually Fibromyalgia was mentioned. I've managed it with rest but rarely painkillers. Since starting your fornula of turmeric I am massively better. It's over 20 years since I was this painfree and not suffering from debilitating exhaustion. I cannot believe I'm soooooo much improved. I want to shout about it to everyone. It's been a miracle for me.

Verified

Gill Rowlands

I took Ibuprofen for over 40 years, trying to control my fibromyalgia and osteoarthritis pain. I knew I needed to stop taking them, but I just couldn't find anything else that worked. Until I started reading about Curcumin. When I found the supplement by Bioroot Labs, I felt it was manufactured in the best way possible, with additions that all the material I read said should be included. I have been taking 3 per day for 4 months now, and I am so happy to say that I am taking NO other pain medication and feel better than I have for many years. My pain and stiffness is not entirely gone, but I am definitely better than I ever was on Ibuprofen. I am a very satisfied customer!

Verified

Sandra Rideout

Before starting this amazing product I had had to give up my business ( upholstery) as I could no longer use my hands through swelling joints I could no longer wear my rings. I think I have been on it about 3 months now and I have my complete use of my hands back. All swelling has gone. Absolutely amazing. The dont click or feel gritty. Thank you

Verified

Tara Crow

I was diagnosed with polymyalgia rhuematica within 6 months I had developed severe ME or CFS. Over the following years I suffered pain and exhaustion and in 2016 eventually Fibromyalgia was mentioned. I've managed it with rest but rarely painkillers. Since starting your fornula of turmeric I am massively better. It's over 20 years since I was this painfree and not suffering from debilitating exhaustion. I cannot believe I'm soooooo much improved. I want to shout about it to everyone. It's been a miracle for me.

Verified

Gill Rowlands

I took Ibuprofen for over 40 years, trying to control my fibromyalgia and osteoarthritis pain. I knew I needed to stop taking them, but I just couldn't find anything else that worked. Until I started reading about Curcumin. When I found the supplement by Bioroot Labs, I felt it was manufactured in the best way possible, with additions that all the material I read said should be included. I have been taking 3 per day for 4 months now, and I am so happy to say that I am taking NO other pain medication and feel better than I have for many years. My pain and stiffness is not entirely gone, but I am definitely better than I ever was on Ibuprofen. I am a very satisfied customer!

Verified

Sandra Rideout

Before starting this amazing product I had had to give up my business ( upholstery) as I could no longer use my hands through swelling joints I could no longer wear my rings. I think I have been on it about 3 months now and I have my complete use of my hands back. All swelling has gone. Absolutely amazing. The dont click or feel gritty. Thank you

Verified

Tara Crow

I was diagnosed with polymyalgia rhuematica within 6 months I had developed severe ME or CFS. Over the following years I suffered pain and exhaustion and in 2016 eventually Fibromyalgia was mentioned. I've managed it with rest but rarely painkillers. Since starting your fornula of turmeric I am massively better. It's over 20 years since I was this painfree and not suffering from debilitating exhaustion. I cannot believe I'm soooooo much improved. I want to shout about it to everyone. It's been a miracle for me.

Verified

Gill Rowlands

I took Ibuprofen for over 40 years, trying to control my fibromyalgia and osteoarthritis pain. I knew I needed to stop taking them, but I just couldn't find anything else that worked. Until I started reading about Curcumin. When I found the supplement by Bioroot Labs, I felt it was manufactured in the best way possible, with additions that all the material I read said should be included. I have been taking 3 per day for 4 months now, and I am so happy to say that I am taking NO other pain medication and feel better than I have for many years. My pain and stiffness is not entirely gone, but I am definitely better than I ever was on Ibuprofen. I am a very satisfied customer!

Verified

Sandra Rideout

Before starting this amazing product I had had to give up my business ( upholstery) as I could no longer use my hands through swelling joints I could no longer wear my rings. I think I have been on it about 3 months now and I have my complete use of my hands back. All swelling has gone. Absolutely amazing. The dont click or feel gritty. Thank you

Verified

Tara Crow

I was diagnosed with polymyalgia rhuematica within 6 months I had developed severe ME or CFS. Over the following years I suffered pain and exhaustion and in 2016 eventually Fibromyalgia was mentioned. I've managed it with rest but rarely painkillers. Since starting your fornula of turmeric I am massively better. It's over 20 years since I was this painfree and not suffering from debilitating exhaustion. I cannot believe I'm soooooo much improved. I want to shout about it to everyone. It's been a miracle for me.

Verified

Gill Rowlands

Take 3 Capsules Daily

Take With Food

Morning Or Evening

Use Consistently for 4–8 Weeks

How To USe

Taking our turmeric supplement is simple, hassle-free, and designed to integrate seamlessly into your daily wellness routine.

Why Turmeric Isn't Optional Anymore

73%

of adults report experiencing muscle or joint pain at least once a week

90%

of turmeric supplements contain weak doses or poor-quality powder

82%

82% of users report feeling less joint stiffness within 30 days

80%

reduction in inflammation markers shown in clinical trials using curcumin

Why Choose BioRoot?

BioRoot

OTHERS

Curcumin Strength

95%

2%

Absorption Boost

Yes

No

3rd Party Lab Tested

Yes

No

Clinically Dosed Extract

Yes

No

Filler Free Formula

Yes

No

  • check_circle60 Day Money Back GuaranteeDon't feel the difference within 60 days? we'll refund you. No questions asked

Have Questions?
We Have Answers.

What makes this turmeric supplement different?

Does turmeric curcumin really help with joint pain and inflammation?

Why does this include black pepper extract?

How long until I see results?

What’s the correct dosage and how should I take it?

Are there any side effects?

Is it safe to take with medications?

How is this better than regular turmeric powder?

Customer Reviews

4.92 out of 5Based on 1509 reviews14187393696.6Sort byMost RecentHighest RatingLowest RatingOnly PicturesPictures FirstVideos FirstMost Helpful06/27/2026Pam McGhie

I'm 70 years old and suffer from chronic pain in both shoulders and lower back. Didn't want to take the very strong medication the doctor prescribed so thought I would try your Turmeric capsules.
Been using them for a couple of months and the results are incredible. I am able to do my gardening, go to the gym and live my life again.
Thank you so much

06/08/2026Mikebholley

I am a retired person currently working part-time to make ends meet, my job is a wheekchair agent at the Orlando International Airport, whereby I transport by foot / wheelchaircustomers fom the front entrance to the airport to their respective plane boarding gtes. This requires a lot of walking to I was having trouble with when I started 60 days ago, but no my joints are not aching in the morning and i can walk several miles again thanks to your product.
Mike H. Orlando

06/04/2026dawn mountain

Was quite sceptical about this at first as I had tried other turmeric supplements in the past with little effect. These however have worked within 2 weeks of taking them my osteoarthritis pain has reduced markedly, leading to me reducing my prescribed pain killers. Very happy with this product highly recommend.

03/27/2026David

Im actually shocked. I've been using Turmeric for 30 days now to help me with a swollen, painful arthritic knee. After 7 to 10 days the swelling went. After 3 weeks the pain eased and now its almost gone completely. Yesterday I walked for 7.5 hours, in snow in the peak district a

. Apart from feeling tired this morning all is good. I even sleep better than before which I didn't realise was related to the pain.

01/21/2026Anonymous

My husband suffers from chronic back pain and I have rheumatoid arthritis so we decided to order these pills because we were both suffering and we were at our wits end about the third day in. We both noticed a difference. It won’t take all your pain and stiffness away, but this Supplement is definitely helping and worth the money. You can really tell that it helps with inflammation.

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Quick links

Disclaimer

These statements have not been evaluated by the Food and Drug Administration or MHRA. These products are not intended to diagnose, treat, cure or prevent any disease.

Support email - info@biorootlabs.com

Phone number +1 (307) 249-4062

Address - 312 W. 2nd St. Casper, WY

Country/region

Lithuania (EUR €)Payment methods

© 2026, Bioroot Labs

Is It Safe?

Yes, EVAYPA uses botanical and nutritional ingredients with prior research and histories of safe use.

Discontinue use and seek medical advice if you develop severe or persistent joint/bone (growth) pain, swelling, or unusually rapid growth.

Ingredients

Each daily serving of 2 capsules provides six concentrated 10:1 extracts, with 200 mg of each ingredient per serving.

Eleuthero Root Extract (10:1) — 200 mg

Equivalent to approximately 2 g of starting root material.

Yeast Hydrolysate (10:1) — 200 mg

Equivalent to approximately 2 g of starting material.

Amomum villosum Fruit Extract (10:1) — 200 mg

Equivalent to approximately 2 g of starting fruit material.

Phyllostachyos Caulis in Taeniam Extract (10:1) — 200 mg

Equivalent to approximately 2 g of starting botanical material.

Velvet Antler Extract (10:1) — 200 mg

Equivalent to approximately 2 g of starting material.

Allium macrostemon Bulb Extract (10:1) — 200 mg

Equivalent to approximately 2 g of starting bulb material.

A 10:1 extract means roughly 10 parts of starting material are used to produce 1 part of extract, so 200 mg of a true 10:1 extract corresponds to about 2 g of starting material.

Serving Size: 2 Capsules

Servings Per Container: 30

Total Capsules: 60

Total Extracts Per Serving: 1,200 mg

Nominal Starting-Material Equivalent: approximately 12 g per serving

Frequently Asked Questions

What is EVAYPA?

EVAYPA is a six-ingredient multi-botanical formula built around ingredients studied in preclinical research for longitudinal skeletal growth, growth-plate activity, GH–IGF-1 signaling, JAK2/STAT5 activation, and related pathways.

How do I take it?

Take 2 capsules daily. Each bottle contains 60 capsules, providing a 30-day supply.

How much of each ingredient is included?

Each daily serving provides 200 mg of each 10:1 extract, for 1,200 mg of total extracts.

What does 10:1 extract mean?

A 10:1 extract means approximately 10 parts of starting material are used to produce 1 part of extract. Therefore, 200 mg of a true 10:1 extract corresponds nominally to about 2 g of starting material.

What ingredients are included?

Eleuthero Root Extract, Yeast Hydrolysate, Amomum villosum Fruit Extract, Phyllostachyos Caulis in Taeniam Extract, Velvet Antler Extract, and Allium macrostemon Bulb Extract.

What research is EVAYPA based on?

The formula was selected around ingredients individually investigated in preclinical studies for effects involving longitudinal bone growth, growth hormone, IGF-1, IGFBP-3, STAT5, BMP-2, chondrocyte proliferation, growth-plate development, and osteogenic activity.

View full details

Every Ingredient Carefully Chosen

Every ingredient in our formula is there for a reason, and backed by peer-reviewed research in mice & rats, not marketing fluff. We don’t hide behind “proprietary blends” or vague labels. You get a clear, transparent list of clinically supported ingredients, each included at a meaningful dose and a 10:1 ratio,

6 selected ingredients

Research summaries are provided for educational context. Findings may come from preclinical studies and should not be interpreted as guaranteed individual outcomes.

EVAYPA ingredient file 0106
Botanical extract
Preclinical research Preclinical evidence

Eleuthero

+75.6% longitudinal bone growth

+75.6% longitudinal bone growth.
Hypertrophic zone ~+27.9%; proliferative zone ~+12.1%; growth-plate IGF-1 ↑, BMP-2 ↑

Study: https://koreantk.com/ktkp2014/thesis/thesis-view.view?ctrlNo=DHBCBU_2003_v18n1_87&tempLang=en

Why it is includedSelected for its complementary role
In the formulaStandardized botanical extract
Inside the formula

The evidence behind
every ingredient

Explore why each ingredient was selected, how it fits the formula, and the research used to inform that choice.

Study type and model are labeled for every ingredient
Ingredient dossier 01 / 06
Formula ingredient
Preclinical study Animal model

Eleuthero

A standout preclinical growth-plate ingredient with unusually strong longitudinal-growth data

Why it’s included

Eleuthero is included as a high-interest preclinical growth-plate ingredient with some of the most striking longitudinal-growth data in the research set. It contributes to the formula’s focus on skeletal-growth and local growth-plate biology.

How it works

Preclinical evidence suggests Eleuthero may act at the level of the growth plate, increasing development of the proliferative and hypertrophic zones while also enhancing local IGF-1 and BMP-2 signaling. This points to a mechanism centered more on local skeletal signaling than simple systemic hormone elevation alone.

In the formula

Eleutherococcus senticosus Root Extract (10:1)

200 mg per serving

Research summaries are provided for educational context. Preclinical or animal-model findings should not be interpreted as demonstrated outcomes in humans. Individual ingredients may perform differently when used in a combined formula.

Customer experiences

Results, in their own words

Filter verified customer experiences by rating, time used, and submitted photos.

4.9

356 reviews

Structured & moderated Submissions are reviewed for authenticity and privacy before publishing.
356 matching reviews
Liam A. Verified review
Used
1 month
Reported
3 cm / month
Age
12
Noah H. Verified review
Used
2 months
Reported
2 cm / month
Age
13
Oliver R. Verified review
Used
3 months
Reported
2 cm / month
Age
14
James B. Verified review
Used
4 months
Reported
2 cm / month
Age
15
Elijah J. Verified review
Used
5 months
Reported
1 cm / month
Age
16
Mateo S. Verified review
Used
6 months
Reported
1 cm / month
Age
17

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